Knoflook reduceert schadelijke effecten van EMV
dinsdag, 05 augustus 2014 - Categorie: Onderzoeken
Bron: informahealthcare.com/doi/abs/10.3109/09553002.2014.922717 .
25 juni 2014
Increased DNA oxidation (8-OHdG) and protein oxidation (AOPP) by low level electromagnetic field (2.45 GHz) in rat brain and protective effect of garlic
International Journal of Radiation Biology
Posted online on June 25, 2014. (doi:10.3109/09553002.2014.922717)
Hatice Ş. Gürler1, Birşen Bilgici1, Ayşegül K. Akar2, Leman Tomak3 & Abdülkerim Bedir1
1Department of Medical Biochemistry, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey
2Department of Biophysics, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey
3Department of Biostatistics and Medical Informatics, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey
Correspondence: Dr Birsen Bilgici, MD, Ondokuz Mayis University, Faculty of Medicine, Department of Medical Biochemistry, 55139, Samsun, Turkey. Tel: + 90 362 3121919/2688. E-mail: email@example.com
Purpose: To investigate the oxidative damage and protective effect of garlic on rats exposed to low level of electromagnetic fields (EMF) at 2.45 GHz Microwave radiation (MWR).
Methods: Thirty-six Wistar rats were divided into three groups. Group I was the control group and not exposed to EMF. Group II and III were exposed to low level EMF (3.68 ± 0.36 V/m) at 2.45 GHz MWR for 1 hour/day for 30 consecutive days. Daily 500 mg/kg garlic was given to Group III during the study period. At the end of the study, thiobarbituric acid reactive substances (TBARS), advanced oxidation protein products (AOPP) and 8-hydroxydeoxyguanosine (8-OHdG) levels were investigated in brain tissue and blood samples.
Results: Exposure to low level of EMF increased 8-OHdG level in both plasma and brain tissue whereas it increased AOPP level only in plasma. Garlic prevented the increase of 8-OHdG level in brain tissue and plasma AOPP levels.
Conclusions: It may be concluded that low level EMF at 2.45 GHz MWR increases the DNA damage in both brain tissues and plasma of the rats whereas it increases protein oxidation only in plasma. It may also be argued that the use of garlic decreases these effects.
Antioxidants, oxidative stress, E-M fields
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