Franse studie: Niet overmatig opwarmende radiofrequente straling geeft verandering DNA sperma.

maandag, 03 november 2008 - Categorie: Onderzoeken

Bron: Gynecol Obstet Fertil. 2008 Oct 27. Epub ahead of print

Het onderhavige onderzoek gaat over het herkennen van fouten in DNA van sperma.
De onderzoekers schrijven dat DNA van sperma ook kan veranderen onder invloed van radiofrequente velden, waarbij het werkingsmechanisme onduidelijk is.
Het is interessant dat de onderzoekers dit stellen, kennelijk achten zij wetenschappelijk voldoende aangetoond dat radiofrequente velden, niet-thermisch en niet-ioniserend, toch DNA kunnen veranderen.

Causes and clinical implications of sperm DNA damages.Article in French

Hazout A, Menezo Y, Madelenat P, Yazbeck C, Selva J, Cohen-Bacrie P.
Service de gyncologie-obsttrique, maternit Aline-de-Crpy, hpital
Bichat-Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris,
France.

Numerous recent studies involve DNA damages associated with poor
fertilization rates, early embryo development defect, and poor quality
of conceptus following Assisted Reproductive Technologies (ART). The
authors denounce a particularly high rate of miscarriages and
childhood cancer or dominant genetic mutations such as achondroplasia,
Apert syndrome or aberrant gene imprinting such as Angelman and
Beckwith Wiedeman syndromes. Gametes DNA defects have numerous origins
which are difficult to determine; they are known to involve
hypomethylation, oxydative stress and environmental factors.(adducts
formation). DNA defect is also linked to a more or less delayed
apoptotic phenomenon. Exposure to radiations or radiofrequency
electromagnetic emissions can also induce DNA alterations into the
spermatozoa of infertile men. Although the underlying mechanisms are
unclear, these DNA defects have obvious consequences on reproduction
of mammalian species. Detection of such anomalies before ART, are an
important step toward developing strategies for clinical management
according to the aetiology.

Voor het originele abstract zie:
www.ncbi.nlm.nih.gov/pubmed/18964175?dopt=AbstractPlus .



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