StopUMTS Logo
how to get rid of moles 
Zoeken
   
Voorlichting
22/01/18ICNIRP Guidelines 1998, E
16/01/18Toon : de 'slimme' thermo
Artikelen
22/01/18WiFi In Schools
22/01/18Literatuur over gezondhei
19/01/18Home networking explained
14/01/18Can Cell Phones Cause Fem
14/01/18Wetenschappers binden str
12/01/18Apple: Open letter from J
Berichten Nederland
22/01/18Computers in een school h
20/01/18Mobiel internetten explod
20/01/18Voorschoten: D66: bescher
18/01/18Unlimited 4G voor thuis g
17/01/18Vergaderlocatie / cursusr
Berichten België
18/01/18Aartselaar / Reet: Buren
10/01/18Vereniging ElektroHyperSe
Berichten Internationaal
15/01/18Frankrijk pakt belabberde
12/01/18Oostenrijk: Richtlijnen v
12/01/18Frankreich verordnet Stra
09/01/18USA: CDPH Cell Phone Safe
Ervaringen | Appellen/oproepen
15/01/18Ziekmakende ervaringen me
12/01/18Soms is tinnitus geen tin
12/01/18Bijnier probleem met smar
Onderzoeken
20/01/18Iron deposition in rabbit
03/01/18EMFs + Wildlife
29/12/17Radiofrequency EMFs and H
Veel gestelde vragen
13/05/17Vakantie? Witte zo
10/07/16Zeven veel gestelde vrage
Juridische informatie
19/01/18Afspraken voor beterere t
01/01/18Antennebeleid op basis va
15/12/17(Persbericht) Phonegate:
Oproepen
10/12/17Haarlem: Raadsmarkt ZENDM
11/11/17Cursus ‘Straling meten
29/10/17Petitie: Geen uitbreiding
Folders
10/09/17Brochures, folders, websi
29/04/16USA: Meer dan 50 tips voo
Briefwisselingen | Archief: 2008, 2005
19/01/18Brief aan Agentschap Tele
18/01/18Brief naar de gemeente Ut
Illustraties
 Algemeen
 Fotoalbum zendmasten
 Wetenschappelijke illustraties
The brain connected to the immune system    
Ga naar overzicht berichten in: Onderzoeken

The brain connected to the immune system
zondag, 17 april 2016 - Dossier: Algemeen


Bron: www.mast-victims.org/index.php?content=news&action=view&type=newsitem&id=7104
en
news.virginia.edu/illimitable/discovery/theyll-have-rewrite-textbooks
21 maart 2016

They’ll Have to Rewrite the Textbooks


USA

It’s a stunning discovery that overturns decades of textbook teaching: researchers at the School of Medicine have determined that the brain is directly connected to the immune system by vessels previously thought not to exist. “I really did not believe there were structures in the body that we were not aware of. I thought the body was mapped,” said Jonathan Kipnis, a professor in the Department of Neuroscience and director of the University’s Center for Brain Immunology and Glia. How these vessels could have escaped detection when the lymphatic system has been so thoroughly mapped throughout the body is surprising on its own.

But the true significance of the discovery lies in its ramifications for the study and treatment of neurological diseases ranging from autism to Alzheimer’s disease to multiple sclerosis. Kipnis said researchers no longer need to ask questions such as, “How do we study the immune response of the brain?” or “Why do multiple sclerosis patients have immune system attacks?” “Now we can approach this mechanistically — because the brain is like every other tissue connected to the peripheral immune system through meningeal lymphatic vessels,” Kipnis said. “We believe that for every neurological disease that has an immune component to it, these vessels may play a major role.” Kevin Lee, who chairs the Department of Neuroscience, recalled his reaction the first time researchers in Kipnis’ lab shared their basic result with him.

“I just said one sentence: ‘They’ll have to rewrite the textbooks.’ There has never been a lymphatic system for the central nervous system, and it was very clear from that first singular observation — and they’ve done many studies since then to bolster the finding — that it will fundamentally change the way people look at the central nervous system’s relationship with the immune system,” Lee said.

The discovery was made possible by the work of Antoine Louveau, a postdoctoral fellow in Kipnis’ lab. The vessels were detected after Louveau developed a method to mount a mouse’s meninges — the membranes covering the brain — on a single slide so that they could be examined as a whole. After noticing vessel-like patterns in the distribution of immune cells on his slides, he tested for lymphatic vessels and there they were. The impossible existed. “Live imaging of these vessels was crucial to demonstrate their function, and it would not be possible without collaboration with Tajie Harris,” Kipnis noted. Harris is an assistant professor of neuroscience and a member of the Center for Brain Immunology and Glia. Kipnis also saluted
the “phenomenal” surgical skills of Igor Smirnov, a research associate in the Kipnis lab whose work was critical to the imaging success of the study.

The unexpected presence of the lymphatic vessels raises a tremendous number of questions that now need answers, both about the workings of the brain and the diseases that plague it. For example, take Alzheimer’s disease. “In Alzheimer’s, there are accumulations of big protein chunks in the brain,” Kipnis said. “We think they may be accumulating in the brain because they’re not being efficiently removed by these vessels.” He noted that the vessels look different with age, so the role they play in aging is another avenue to explore. And there’s an enormous array of other neurological diseases, from autism to multiple sclerosis, that must be reconsidered in light of the presence of something science insisted did not exist.


Ga terug naar het hoofdmenu
Afdrukken | Vragen | RSS | Disclaimer